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Women's health — education

HPV vaccine: what it does, who it is for, and what it does not replace.

Human Papillomavirus (HPV) is a common infection linked to cervical cancer. The HPV vaccine reduces the risk of HPV-related disease — but vaccination and cervical screening work best together, not in place of each other.

Medically reviewed by Dr. Shweta Agarwal, MBBS, DGO · Last updated July 2026
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Understanding HPV

What is Human Papillomavirus (HPV)?

Human Papillomavirus (HPV) is a group of more than 200 related viruses, spread primarily through skin-to-skin contact. Most HPV infections clear on their own without symptoms. However, certain "high-risk" strains — particularly HPV 16 and HPV 18 — can persist and, over many years, cause cellular changes that may develop into cervical cancer or other cancers (vulvar, vaginal, anal, oropharyngeal).

Cervical cancer is among the more preventable cancers because it typically progresses slowly through detectable precancerous stages, and both vaccination (to reduce initial infection) and regular screening (to detect early changes) are effective public-health tools.

What the vaccine does

What does the HPV vaccine protect against?

Cervical cancer risk reduction

The HPV vaccine reduces the risk of cervical cancer caused by the high-risk strains it covers. HPV 16 and 18 together account for approximately 70% of cervical cancers. Vaccines targeting these strains have demonstrated significant reductions in precancerous cervical lesions in large clinical trials and real-world programmes.

Genital warts (low-risk strains)

The quadrivalent (4-strain) and nonavalent (9-strain) vaccines also protect against HPV 6 and 11, the strains responsible for most cases of genital warts. The bivalent (2-strain) vaccine does not include these strains.

What the vaccine does not do

The HPV vaccine does not treat existing HPV infection or existing cervical abnormalities. It does not cover all HPV strains. Protection is strongest when given before any exposure to the virus — it is not a therapeutic (treatment) vaccine. It is a preventive vaccine.

Screening is still essential

Even fully vaccinated women should continue regular cervical screening (Pap smear or HPV test) according to the schedule recommended by their doctor, because the vaccine does not cover all cancer-causing HPV strains.

Vaccines available in India

Which HPV vaccines are available, and what do they cost?

Three HPV vaccines are available in India. The figures below are the manufacturer's MRP per dose as of 2026 — MRP is set by the manufacturer and may change over time, and the actual price you pay at a pharmacy can be lower. The number of doses depends on age.

VaccineStrains coveredMRP (per dose)Notes
Cervavac
Serum Institute of India
4-strain (6, 11, 16, 18) ₹2,000 Indigenous quadrivalent vaccine. Provided free for girls aged 9–14 under the national immunisation programme where available.
Gardasil 4
MSD
4-strain (6, 11, 16, 18) ₹3,927 Quadrivalent; an older vaccine now being phased out and replaced by Gardasil 9 in many markets — availability may be limited.
Gardasil 9
MSD
9-strain (6, 11, 16, 18, 31, 33, 45, 52, 58) ₹10,850 Nonavalent — covers the widest range of high-risk strains. The most expensive option.

How many doses are needed?

Dosing depends on age at the first dose: 2 doses for ages 9–14, and 3 doses for ages 15–26. The full course cost is the per-dose price multiplied by the number of doses — so a Gardasil 9 course costs considerably more than a Cervavac course. Your doctor confirms the right schedule for you.

A note on price vs. protection

A higher-valent vaccine covers more strains but all licensed HPV vaccines protect against HPV 16 and 18 — the two types behind roughly 70% of cervical cancers. Which vaccine is appropriate is a decision to make with your doctor based on age, budget and availability, not on price alone.

MRP figures are set by the manufacturer and may change over time; they do not represent a quotation from Aansh. Availability of a specific vaccine at any given time is not guaranteed. Please confirm current price and stock at the time of consultation.

Who and when

Who is the HPV vaccine recommended for?

Protection is strongest when vaccination is completed before exposure to HPV. Public-health guidance generally recommends:

  • Primary target group: Girls aged 9–14 years — before the onset of sexual activity.
  • Catch-up vaccination: Adolescent girls and women up to age 26 (and in some guidelines up to age 45) who have not previously been vaccinated.
  • Adult women: Women beyond the primary target age may benefit from vaccination after discussion with their doctor, though evidence of benefit generally decreases with age and prior exposure.

The appropriate vaccine type (bivalent, quadrivalent or nonavalent), dosing schedule, and whether vaccination is appropriate for you are decisions to make with your doctor based on your age and history.

At Aansh

Cervical health services

Dr. Shweta Agarwal (MBBS, DGO) provides women's health consultations including discussion of HPV vaccination and cervical cancer screening.

Medical note: Information on this page is educational and does not replace a medical consultation. Outcomes depend on individual clinical factors. Last updated July 2026.

Good to know

Frequently asked questions about the HPV vaccine

What is the HPV vaccine?
The HPV vaccine is a vaccine that protects against infection by certain high-risk strains of Human Papillomavirus (HPV) — the strains most associated with cervical cancer and some other HPV-related cancers. Currently available HPV vaccines protect against either 2, 4 or 9 strains of HPV. The vaccines work by stimulating the immune system to produce antibodies before any exposure to the virus, so the body is prepared if exposed later.
Who should get the HPV vaccine?
HPV vaccination is recommended primarily for girls and women before the onset of sexual activity, as protection is strongest when given before potential exposure to HPV. National immunisation schedules vary; current public-health guidance in India recommends vaccination for girls aged 9–14 years as the primary target group, with catch-up vaccination recommended up to age 26 in many guidelines. Vaccination may also be considered for adults beyond this range following discussion with a doctor. Your doctor can advise on the appropriate schedule and vaccine for your situation.
Does the HPV vaccine prevent cervical cancer?
The HPV vaccine significantly reduces the risk of cervical cancer caused by the HPV strains it covers. Clinical evidence shows it reduces the incidence of precancerous cervical lesions (CIN 2/3) caused by high-risk HPV types, particularly HPV 16 and 18, which together account for the majority of cervical cancer cases. However, no vaccine provides 100% protection — it does not cover all HPV strains, and it does not treat existing HPV infection. Regular cervical screening (Pap smear / HPV test) remains important even after vaccination.
How much does the HPV vaccine cost in India?
Cost depends on which vaccine is used and how many doses are needed. As of 2026, the manufacturer's MRP per dose is around ₹2,000 for Cervavac (Serum Institute, 4-strain), ₹3,927 for Gardasil 4 (MSD, 4-strain, limited availability) and ₹10,850 for Gardasil 9 (MSD, 9-strain). MRP is set by the manufacturer and may change over time, and the actual pharmacy price can be lower. Two doses are given for ages 9–14 and three doses for ages 15–26. Under the national immunisation programme, Cervavac is provided free for girls aged 9–14 where available. Confirm current price and stock at the time of consultation.
Is cervical screening still needed after vaccination?
Yes. Cervical screening (Pap smear or HPV test) is recommended even after vaccination, because no HPV vaccine covers all cancer-causing HPV strains. Screening can detect precancerous changes caused by strains not in the vaccine, as well as any changes in women who were already exposed to HPV before vaccination. Follow the cervical-screening schedule recommended by your doctor — vaccination and screening work together, not in place of each other.
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